| GSAS
Harvard Biotechnology Club Business Plan Competition |
June
2005
Sponsored by:



These are the entries to the 6th Annual Biotechnology Business Plan Competition:
*Claros
Diagnostics* | *Vascular
Precision*
Affinity
Vision | Amorigen
Pharmaceuticals | BioSignetics
Cure Works |
Corinova Incorporated | Herck
Biotech | ImmunoGenetix Therapeutics
Keren Pharmaceuticals |
Linguaflex |
Microbiobotics
Molecular Creativity, Inc. |
Osio Corporation | Previva,
Inc
SeeScienceRun | SimuGen
!!!
WINNERS ANNOUNCED !!!
Congratulations to First Place Claros Diagnostics!!!
and
Second Place Vascular Precision!!!
Claros
Diagnostics - ! FIRST PLACE !
Contact: David Steinmiller
David.Steinmiller@ClarosDx.com
Claros Diagnostics has developed a handheld device that will revolutionize
disease monitoring by allowing anyone to perform laboratory-quality blood
tests in any setting. Based on patented technology from the Harvard laboratory
of George Whitesides, this system reduces diagnosis time from days to
minutes, eliminates the need for technical expertise, and cuts out 99%
of capital costs. Claros will produce a rapid test of multiple diseases
for the $3 billion sexually transmitted disease market and further develop
the system for large segments of the $21 billion market for in-vitro diagnostics.
[ back to top ]
Affinity Vision
Contact: David Bergstein
David.Bergstein.2002@alum.bu.edu
Affinity Vision is revolutionizing microarray use with label-free
detection technologies. Our microarray detection technologies free
scientists and doctors from the burden of labeling their molecular
targets. Avoiding the need to label saves time, money, and most importantly,
opens the door to many new and exciting applications for microarrays.
[ back to top ]
Amorigen Pharmaceuticals
Contact: John J. Frey
jfrey@hpdtech.com
Amorigen Pharmaceuticals is developing a predictive-pharmacology-driven
product pipeline engine of repositioned prescription drugs treating
psychiatric or psychological conditions with quality-of-life or lifestyle
ramifications, targeting unmet medical needs (no present FDA approved
therapy) with potential to be first-in-class. Now ready to advance
into phase 2 clinical trials by leveraging the existing IND (Investigational
New Drug dossier filed with the FDA) for a compound that has been
marketed for a distinct indication (no generic competition due to
a patented form-of-administration), based on our pending use-patent
for low-dose, p.r.n.- administered drug that treats the psychogenic
root-cause of four related disorders, each with peak annual revenue
potential of up to or exceeding $500 million. We are currently negotiating
a global Pharma strategic partnership that funds launch and sales/marketing,
and we receive development milestone payments plus significant royalty-on-salesin
addition to co-marketing rights; thus we expect to achieve profitability
by year-four.
[ back to top ]
BioSignetics
Contact: Vladimir Polyshcuk, Ph.D.
vladpoly@bsignetics.com
BioSignetics – The Digital Stethoscope Company - is a New Hampshire
based venture offering a new revolutionary system for the low cost and
non-invasive diagnosis of early stage heart disease. The company is seeking
up to $5 million in venture capital to launch the new BioSignetics Stethoscope
Software – A Non-Invasive Early Warning System for Heart Disease.
Initial product market estimate for the product is $2.2 billion in US
alone.
[ back to top ]
CorInnova, Inc.
Contact: Dr. John C. Criscione
Corinnova@cox-internet.com
CorInnova Incorporated is an early stage biomedical device company
that is engaged in the development of technologies that lead to heart
recovery. In particular, recent discoveries indicate that aberrant
heart motions such
as dyskinesis and hypokinesis can lead to muscle cell death, fibrosis,
infarct expansion, and heart failure; whereas restoration of normal
cardiac motion can preserve vulnerable heart tissue and promote recovery.
Our approach is called Cardiac ReKinesis (CRK) Therapy; and to so
treat the annual 70,000 vulnerable, bedridden Americans with severe
cardiac dyskinesis, we have developed the CRK Pocket, an active direct
cardiac compression device that can be implanted and explanted in
a minimally invasive fashion.
[ back to top ]
Malaria is one of the most severe public health problems in the world.
There is no known cure for the disease and current treatments are ineffective
and insufficient. CureWorks, Inc. has identified a novel approach to
developing a malaria vaccine based on cutting-edge nanoscale drug-delivery
technology. CureWorks, Inc. will initially target the rapidly growing
travelers’ vaccine market and then use the expertise developed
to extend into other vaccine and therapeutic applications.
[ back to top ]
Herck Biotechnology
Contact: Zhe Zhou
zhezhou@fas.harvard.edu
Herck Biotech., founded by enthusiastic medicinal biochemists,
aims at isolating, identifying, characterizing and marketing anti-acne
compounds from traditional Chinese medicine (TCM), with the help
of TCM literature and empirical prescriptions. An extensive library
from TCM will be established and marketed as well in order to help
future discovery for Herck Biotech. and other pharmaceuticals. A
profit of 20 million dollars per year is expected after marketing,
with an increase of 5-10% per year.
[ back to top ]
ImmunoGenetix Therapeutics
Contact: Jim Laufenberg
lauf1@earthlink.com
ImmunoGenetix Therapeutics, Inc. is an early stage biotechnology company
developing advanced DNA-based therapies for the treatment of viral infections,
with a focus on HIV, and has exclusive worldwide rights to proprietary
therapeutic candidates being developed at the University of Kansas Medical
Center. A lead candidate has completed initial efficacy studies in monkeys
with promising results. The company is now prepared to process a Proposal
for a major NIH drug development contract in order to complete an IND
submission.
[ back to top ]
Keren Pharmaceuticals
Contact: David Dreyfuss
dhdreyfus@pol.net
Keren Pharmaceutical is a seed stage biotechnology company that uses
EGS (External Guide Sequence) RNA enzyme technology to develop inhaled
drugs for influenza, asthma and other respiratory diseases. It has exclusive
rights from Yale University to the technology, which was developed by
Nobel Prize winner Sidney Altman.
[ back to top ]
Linguaflex
Contact: Andrew Scirri
andrewscirri@yahoo.com
Linguaflex is a medical device company that will develop, manufacture
and distribute novel medical devices for the treatment of sleep apnea.
Our goal is to be the market leader in providing minimally invasive
treatments that address the root cause of sleep apnea. The initial company
focus is on product development and gaining FDA approval. Linguaflex
will also market and sell complementary and peripheral products for
our device.
[ back to top ]
Microbiobotics
Contact: Alexander Kim
mbb@kirns.de
MBB will release the Cell Surgeon as its flagship product. It eliminates
the incredibly tedious, unreliable, often cell-damaging and expensive
process that biologists face. We envision becoming a leader for MEMS
robotics by building a technology platform with our fundamental patents
and integrate tools for specific markets such as agriculture, tissue
engineering, genomics and personalized medicine.
[ back to top ]
Molecular Creativity
Contact: David R. Bachinsky
dbachinsky@comcast.net
Molecular Creativity, Inc. is dedicated to providing unique DNA products
and services. Internal research and development at Molecular Creativity,Inc.
has focused on a novel, two compartment approach to storage of biologicals.
Core technologies are focused on the storage of DNA and other biologicals
with applications to multiple markets including medical, military, forensics,
biobanks and Jewelry.
[ back to top ]
Osio Corporation
Contact: Alberto Osio
alosio@sloan.mit.edu
Osio Corp's patent pending Topical Presbyopia Procedure (TOPP) is
the only safe, non-invasive and effective procedure available to treat
presbyopes or "short arms disease" (up-close vision loss)
using an ingenious combination of personalized contact lenses, specially
formulated eye drops and integrating specification software. TOPP has
already completed the discovery phase and controlled trials with 150
successful treatments under the supervision of its inventor. The next
stage of development will be to pursue United States Food and Drug Administration
(FDA) approval before
launching commercially to every optical retail outlets (i.e. Lens Crafters)
and eye clinics across the US.
[ back to top ]
Previva, Inc.
Contact: Murat Kalayoglu
murat_k@mit.edu
Previva, Inc. develops real-time, remote systems to monitor patients’
medication use and prevent complications from chronic diseases. Our
lead product, VentStar, controls asthma and similar pulmonary diseases
that afflict 24 million Americans and incur annual costs of over $27
billion. VentStar uses a proprietary “smart inhaler” to
predict asthma attacks and prevent them with early, low-cost interventions.
VentStar saves lives, reduces hospital admissions, and reduces healthcare
costs while building a substantial and forecastable recurring revenue
stream. Previva represents an excellent opportunity to build a profitable
business on a chronic disease population that will double by 2020.
[ back to top ]
SeeScienceRun
Contact: Philip Dreyfuss
dreyfuss@fas.harvard.edu
Protocols are the recipes for scientific experiments. Just as the average
cook has difficulty following the written recipe of a master chef, it
is challenging and often impossible for scientists to take a text-based
protocol and get the desired experimental result. Performing a scientific
procedure for the first time or reproducing a protocol from the scientific
literature can be an extremely time consuming and frustrating experience.
SeeScienceRun.com seeks to alleviate this difficulty by taking advantage
of the fact that many key aspects of experimental protocols can be more
readily conveyed visually than through words. We will produce, sell
and distribute high quality streaming demonstration videos that illustrate
fundamental and modern experimental techniques.
[ back to top ]
SimuGen
Contact: Daniel Sheehan
ds394@cam.ac.uk
SimuGen is a gene profiling company, implementing novel techniques
from the field of Computational Biology and bringing to market a kit
that can determine substance toxicity cheaper, faster and better than
animal models.
[ back to top ]
|
| 2005 Judges |
|
Doug Cole
General Partner,
Flagship Ventures
Brian Atwood Managing Partner,
Versant Ventures
John Choi
Principle, Venrock Associates
Zack Jonasson
Principle, Seaflower Ventures
Peter Finn, J.D.
Senior Partner, Head of Biotechnology Group Rubin
and Rudman, LLP
Steve Wardell Principal,
CPP Capital, LLC
Michael Lytton, M.Sc., J.D.
General Partner, Oxford Bioscience
Partners
Earl Weinstein
Associate, PureTech Ventures
Anita Hoffer, Ph.D.
Consultant, Hoffer Associates |
|