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GSAS Harvard Biotechnology Club Business Plan Competition

June 2005

 

Sponsored by:










These are the entries to the 6th Annual Biotechnology Business Plan Competition:

*Claros Diagnostics* | *Vascular Precision*

Affinity Vision | Amorigen Pharmaceuticals | BioSignetics

Cure Works | Corinova Incorporated  | Herck Biotech | ImmunoGenetix Therapeutics
Keren Pharmaceuticals | Linguaflex | Microbiobotics
Molecular Creativity, Inc. | Osio Corporation | Previva, Inc
SeeScienceRun | SimuGen

!!! WINNERS ANNOUNCED !!!

 

Congratulations to First Place Claros Diagnostics!!! and

Second Place Vascular Precision!!!


Claros Diagnostics - ! FIRST PLACE !
Contact: David Steinmiller

David.Steinmiller@ClarosDx.com

Claros Diagnostics has developed a handheld device that will revolutionize disease monitoring by allowing anyone to perform laboratory-quality blood tests in any setting. Based on patented technology from the Harvard laboratory of George Whitesides, this system reduces diagnosis time from days to minutes, eliminates the need for technical expertise, and cuts out 99% of capital costs. Claros will produce a rapid test of multiple diseases for the $3 billion sexually transmitted disease market and further develop the system for large segments of the $21 billion market for in-vitro diagnostics.

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Vascular Precision- ! SECOND PLACE !
Contact: Michael Gober

gober_michael@gsb.stanford.edu

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Affinity Vision
Contact: David Bergstein
David.Bergstein.2002@alum.bu.edu

Affinity Vision is revolutionizing microarray use with label-free detection technologies. Our microarray detection technologies free scientists and doctors from the burden of labeling their molecular targets. Avoiding the need to label saves time, money, and most importantly, opens the door to many new and exciting applications for microarrays.
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Amorigen Pharmaceuticals
Contact: John J. Frey

jfrey@hpdtech.com

Amorigen Pharmaceuticals is developing a predictive-pharmacology-driven product pipeline engine of repositioned prescription drugs treating psychiatric or psychological conditions with quality-of-life or lifestyle ramifications, targeting unmet medical needs (no present FDA approved therapy) with potential to be first-in-class. Now ready to advance into phase 2 clinical trials by leveraging the existing IND (Investigational New Drug dossier filed with the FDA) for a compound that has been marketed for a distinct indication (no generic competition due to a patented form-of-administration), based on our pending use-patent for low-dose, p.r.n.- administered drug that treats the psychogenic root-cause of four related disorders, each with peak annual revenue potential of up to or exceeding $500 million. We are currently negotiating a global Pharma strategic partnership that funds launch and sales/marketing, and we receive development milestone payments plus significant royalty-on-salesin addition to co-marketing rights; thus we expect to achieve profitability
by year-four.
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BioSignetics
Contact: Vladimir Polyshcuk, Ph.D.

vladpoly@bsignetics.com

BioSignetics – The Digital Stethoscope Company - is a New Hampshire based venture offering a new revolutionary system for the low cost and non-invasive diagnosis of early stage heart disease. The company is seeking up to $5 million in venture capital to launch the new BioSignetics Stethoscope Software – A Non-Invasive Early Warning System for Heart Disease. Initial product market estimate for the product is $2.2 billion in US alone.
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CorInnova, Inc.
Contact: Dr. John C. Criscione

Corinnova@cox-internet.com

CorInnova Incorporated is an early stage biomedical device company that is engaged in the development of technologies that lead to heart recovery. In particular, recent discoveries indicate that aberrant heart motions such
as dyskinesis and hypokinesis can lead to muscle cell death, fibrosis, infarct expansion, and heart failure; whereas restoration of normal cardiac motion can preserve vulnerable heart tissue and promote recovery. Our approach is called Cardiac ReKinesis (CRK) Therapy; and to so treat the annual 70,000 vulnerable, bedridden Americans with severe cardiac dyskinesis, we have developed the CRK Pocket, an active direct cardiac compression device that can be implanted and explanted in a minimally invasive fashion.
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Cure Works
Product/Service: Vaccine Formulation Venture
Contact:
Philip Dreyfuss
dreyfuss@fas.harvard.edu

Malaria is one of the most severe public health problems in the world. There is no known cure for the disease and current treatments are ineffective and insufficient. CureWorks, Inc. has identified a novel approach to developing a malaria vaccine based on cutting-edge nanoscale drug-delivery technology. CureWorks, Inc. will initially target the rapidly growing travelers’ vaccine market and then use the expertise developed to extend into other vaccine and therapeutic applications.
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Herck Biotechnology
Contact: Zhe Zhou

zhezhou@fas.harvard.edu

Herck Biotech., founded by enthusiastic medicinal biochemists, aims at isolating, identifying, characterizing and marketing anti-acne compounds from traditional Chinese medicine (TCM), with the help of TCM literature and empirical prescriptions. An extensive library from TCM will be established and marketed as well in order to help future discovery for Herck Biotech. and other pharmaceuticals. A profit of 20 million dollars per year is expected after marketing, with an increase of 5-10% per year.
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ImmunoGenetix Therapeutics
Contact: Jim Laufenberg
lauf1@earthlink.com

ImmunoGenetix Therapeutics, Inc. is an early stage biotechnology company developing advanced DNA-based therapies for the treatment of viral infections, with a focus on HIV, and has exclusive worldwide rights to proprietary therapeutic candidates being developed at the University of Kansas Medical Center. A lead candidate has completed initial efficacy studies in monkeys with promising results. The company is now prepared to process a Proposal for a major NIH drug development contract in order to complete an IND submission.
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Keren Pharmaceuticals
Contact: David Dreyfuss

dhdreyfus@pol.net

Keren Pharmaceutical is a seed stage biotechnology company that uses EGS (External Guide Sequence) RNA enzyme technology to develop inhaled drugs for influenza, asthma and other respiratory diseases. It has exclusive rights from Yale University to the technology, which was developed by Nobel Prize winner Sidney Altman.
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Linguaflex
Contact: Andrew Scirri

andrewscirri@yahoo.com

Linguaflex is a medical device company that will develop, manufacture and distribute novel medical devices for the treatment of sleep apnea. Our goal is to be the market leader in providing minimally invasive treatments that address the root cause of sleep apnea. The initial company focus is on product development and gaining FDA approval. Linguaflex will also market and sell complementary and peripheral products for our device.
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Microbiobotics
Contact: Alexander Kim

mbb@kirns.de

MBB will release the Cell Surgeon as its flagship product. It eliminates the incredibly tedious, unreliable, often cell-damaging and expensive process that biologists face. We envision becoming a leader for MEMS robotics by building a technology platform with our fundamental patents and integrate tools for specific markets such as agriculture, tissue engineering, genomics and personalized medicine.
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Molecular Creativity
Contact: David R. Bachinsky

dbachinsky@comcast.net

Molecular Creativity, Inc. is dedicated to providing unique DNA products and services. Internal research and development at Molecular Creativity,Inc. has focused on a novel, two compartment approach to storage of biologicals. Core technologies are focused on the storage of DNA and other biologicals with applications to multiple markets including medical, military, forensics, biobanks and Jewelry.
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Osio Corporation
Contact: Alberto Osio

alosio@sloan.mit.edu

Osio Corp's patent pending Topical Presbyopia Procedure (TOPP) is the only safe, non-invasive and effective procedure available to treat presbyopes or "short arms disease" (up-close vision loss) using an ingenious combination of personalized contact lenses, specially formulated eye drops and integrating specification software. TOPP has already completed the discovery phase and controlled trials with 150 successful treatments under the supervision of its inventor. The next stage of development will be to pursue United States Food and Drug Administration (FDA) approval before
launching commercially to every optical retail outlets (i.e. Lens Crafters) and eye clinics across the US.
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Previva, Inc.
Contact: Murat Kalayoglu

murat_k@mit.edu

Previva, Inc. develops real-time, remote systems to monitor patients’ medication use and prevent complications from chronic diseases. Our lead product, VentStar, controls asthma and similar pulmonary diseases that afflict 24 million Americans and incur annual costs of over $27 billion. VentStar uses a proprietary “smart inhaler” to predict asthma attacks and prevent them with early, low-cost interventions. VentStar saves lives, reduces hospital admissions, and reduces healthcare costs while building a substantial and forecastable recurring revenue stream. Previva represents an excellent opportunity to build a profitable business on a chronic disease population that will double by 2020.
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SeeScienceRun
Contact: Philip Dreyfuss

dreyfuss@fas.harvard.edu

Protocols are the recipes for scientific experiments. Just as the average cook has difficulty following the written recipe of a master chef, it is challenging and often impossible for scientists to take a text-based protocol and get the desired experimental result. Performing a scientific procedure for the first time or reproducing a protocol from the scientific literature can be an extremely time consuming and frustrating experience. SeeScienceRun.com seeks to alleviate this difficulty by taking advantage of the fact that many key aspects of experimental protocols can be more readily conveyed visually than through words. We will produce, sell and distribute high quality streaming demonstration videos that illustrate fundamental and modern experimental techniques.
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SimuGen
Contact: Daniel Sheehan

ds394@cam.ac.uk

SimuGen is a gene profiling company, implementing novel techniques from the field of Computational Biology and bringing to market a kit that can determine substance toxicity cheaper, faster and better than animal models.
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Past Competitions

2005

2004

2003

2002

2001

2000

Index

2005 Judges

Doug Cole
General Partner, Flagship Ventures

Brian Atwood
Managing Partner, Versant Ventures

John Choi
Principle, Venrock Associates

Zack Jonasson
Principle, Seaflower Ventures

Peter Finn, J.D.
Senior Partner, Head of Biotechnology Group
Rubin and Rudman, LLP

Steve Wardell
Principal, CPP Capital, LLC

Michael Lytton, M.Sc., J.D.
General Partner, Oxford Bioscience Partners

Earl Weinstein
Associate, PureTech Ventures

Anita Hoffer, Ph.D.
Consultant, Hoffer Associates